Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533117 | 0.82 | LMNA (0.58) | IDO1MGLLPKMLMNASMN1; SMN2 | |
| SCHEMBL9528281 | 0.82 | LMNA (0.58) | IDO1MGLLPKMLMNASMN1; SMN2 | |
| SCHEMBL10513899 | 0.82 | LMNA (0.58) | IDO1MGLLPKMLMNASMN1; SMN2 | |
| SCHEMBL17956746 | 0.82 | LMNA (0.58) | IDO1MGLLPKMLMNASMN1; SMN2 | |
| SCHEMBL18695165 | 0.79 | LMNA (0.66) | IDO1MGLLPKMLMNASMN1; SMN2 | |
| SCHEMBL15480393 | 0.79 | PGR (0.65) | PGRLMNASMN1; SMN2HTTPSMB11 | |
| SCHEMBL20777973 | 0.79 | PGR (0.65) | PGRLMNASMN1; SMN2HTTPSMB11 | |
| SCHEMBL17956781 | 0.76 | TSHR (0.64) | IDO1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11072625 | 0.75 | IDO1 (0.62) | IDO1PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20777912 | 0.75 | PSMB11 (0.72) | PGRALDH1A1MAPTPSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |