Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533117 | 1.00 | LMNA (0.58) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL10513899 | 1.00 | LMNA (0.58) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL17956746 | 1.00 | LMNA (0.58) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL18695165 | 0.94 | LMNA (0.66) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL9230075 | 0.93 | IDO1 (0.60) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL1638316 | 0.87 | NPC1 (0.54) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL7157543 | 0.83 | EPHX1 (0.67) | HTTMGLLALDH1A1 | |
| SCHEMBL17079618 | 0.83 | EPHX1 (0.67) | HTTMGLLALDH1A1 | |
| SCHEMBL8443237 | 0.82 | LMNA (0.65) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL8391699 | 0.82 | LMNA (0.65) | LMNASMN1; SMN2KMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10767112-B2 | Methods of producing metal sulfides, metal selenides, and metal sulfides/selenides having controlled architectures using kinetic control | THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-09-08 | — | — | US | disclosed |
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-04-09 | — | — | US | disclosed |
| CN-106103348-B | The purposes of sulphur compound and selenium compound as the precursor of nano structural material | 哥伦比亚大学（纽约）理事会 | 2018-07-31 | — | — | CN | disclosed |
| US-20170369779-A1 | METHODS OF PRODUCING METAL SULFIDES, METAL SELENIDES, AND METAL SULFIDES/SELENIDES HAVING CONTROLLED ARCHITECTURES USING KINETIC CONTROL | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-12-28 | — | — | US | disclosed |
| CN-106103348-A | Sulphur compound and selenium compound are as the purposes of the precursor of nano structural material | 哥伦比亚大学（纽约）理事会 | 2016-11-09 | — | — | CN | disclosed |
| US-20160237345-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160237345-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-08-18 | — | — | US | disclosed |
| EP-3049370-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | The Trustees of Columbia University in the City of New York (US) | 2016-08-03 | — | — | EP | disclosed |
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | SCLY, TST, SOD1 | LMNA 3945/4885SMN1; SMN2 90/4885KMT2A 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.