Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784164 | 0.82 | FBP1 (0.69) | MAPK1NPSR1PKMPAX8ATM | |
| SCHEMBL28461028 | 0.82 | ALDH1A1 (0.53) | MAPK1NPSR1PKMPAX8ATM | |
| SCHEMBL10535557 | 0.81 | FBP1 (0.72) | MAPK1NPSR1FBP1ALDH1A1HSD17B10 | |
| SCHEMBL28460942 | 0.81 | FBP1 (0.49) | MAPK1NPSR1PKMPAX8ATM | |
| SCHEMBL28451176 | 0.80 | KDM4E (0.50) | MAPK1NPSR1PKMPAX8ATM | |
| SCHEMBL28451878 | 0.79 | NPSR1 (0.52) | MAPK1NPSR1PKMPAX8ATM | |
| SCHEMBL28455463 | 0.77 | FBP1 (0.45) | MAPK1NPSR1PKMPAX8ATM | |
| SCHEMBL28460988 | 0.77 | ALDH1A1 (0.54) | MAPK1NPSR1FBP1ALDH1A1HSD17B10 | |
| SCHEMBL28353371 | 0.76 | MAPT (0.53) | NPSR1PKMALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28353372 | 0.74 | HDAC6 (0.64) | NPSR1PKMATMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166159-B | Compounds having PDE9A inhibiting activity and pharmaceutical uses thereof | 韩国化学研究院 | 2023-10-24 | — | — | CN | disclosed |
| CN-113166159-A | Compound with PDE9A inhibitory activity and pharmaceutical use thereof | 韩国化学研究院 | 2021-07-23 | — | — | CN | disclosed |
| CN-107602548-B | Myricetin derivative containing amide thioether thiadiazole, preparation method and application | 贵州大学 | 2020-09-01 | — | — | CN | disclosed |
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0036081-A1 | Azo dyestuffs as well as their preparation and their use in dyeing synthetic fibres | BAYER AG (DE) | 1981-09-23 | — | — | EP | disclosed |
| US-4001203-A | Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |