Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449149 | 0.81 | PKM (0.48) | EPHX2SCN4APKMMAPK1PAX8 | |
| SCHEMBL28460942 | 0.81 | FBP1 (0.49) | FBP1ALDH1A1PKMMAPK1PAX8 | |
| SCHEMBL28461028 | 0.79 | ALDH1A1 (0.53) | FBP1ALDH1A1PKMMAPK1PAX8 | |
| SCHEMBL10535557 | 0.77 | FBP1 (0.72) | FBP1ALDH1A1MAPK1NPSR1LMNA | |
| SCHEMBL9530474 | 0.77 | MAPK1 (0.53) | FBP1ALDH1A1PKMMAPK1PAX8 | |
| SCHEMBL27982917 | 0.76 | NPC1 (0.54) | ALDH1A1MAPK1HSD17B10MAPT | |
| SCHEMBL28460988 | 0.73 | ALDH1A1 (0.54) | FBP1ALDH1A1DHFRTP53MAPK1 | |
| SCHEMBL10532529 | 0.71 | MAPT (0.58) | FBP1ALDH1A1DHFRTP53PKM | |
| SCHEMBL2417142 | 0.71 | HAO1 (0.53) | FBP1HAO1ALDH1A1DHFR | |
| SCHEMBL20214353 | 0.70 | KDM4E (0.69) | ALDH1A1MKNK1MKNK2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602548-B | Myricetin derivative containing amide thioether thiadiazole, preparation method and application | 贵州大学 | 2020-09-01 | — | — | CN | disclosed |