Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532312 | 0.98 | ABCG2 (0.33) | ALDH1A1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL9533854 | 0.90 | ABCG2 (0.36) | ABCG2ITGB2ICAM1ITGALHTR2C | |
| SCHEMBL9532164 | 0.71 | ABCG2 (0.36) | ABCG2ITGB2ICAM1ITGALCHRM2 | |
| SCHEMBL22978927 | 0.68 | ALOX5 (0.35) | ABCG2ITGB2ICAM1ITGALCHRM2 | |
| SCHEMBL9531663 | 0.67 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9531618 | 0.67 | ABCG2 (0.32) | ABCG2ITGB2ICAM1ITGALCHRM2 | |
| SCHEMBL10389872 | 0.67 | CHRM2 (0.33) | ABCG2ITGB2ICAM1ITGALCHRM2 | |
| SCHEMBL9533561 | 0.66 | HTR1A (0.33) | ABCG2ITGB2ICAM1ITGALCHRM2 | |
| SCHEMBL15144578 | 0.65 | TNKS (0.43) | ALDH1A1ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL9532845 | 0.64 | CHRM2 (0.31) | ABCG2ITGB2ICAM1ITGALCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |