Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625352 | 0.75 | SIGMAR1 (0.43) | SIGMAR1NISCHMAOAMAOBHSD17B3 | |
| SCHEMBL31325075 | 0.75 | SIGMAR1 (0.46) | SIGMAR1NISCHMAOAMAOBHSD17B3 | |
| SCHEMBL28242590 | 0.75 | SIGMAR1 (0.43) | SIGMAR1NISCHMAOAMAOBHSD17B3 | |
| SCHEMBL4854732 | 0.75 | SIGMAR1 (0.43) | SIGMAR1NISCHMAOAMAOBHSD17B3 | |
| SCHEMBL31633760 | 0.74 | SIGMAR1 (0.40) | SIGMAR1NISCHHSD17B3 | |
| SCHEMBL10965410 | 0.73 | SIGMAR1 (0.45) | SIGMAR1NISCHMAOAMAOBHSD17B3 | |
| SCHEMBL30005029 | 0.72 | SIGMAR1 (0.44) | SIGMAR1NISCHMAOAMAOBHSD17B3 | |
| SCHEMBL11009587 | 0.71 | ALOX5 (0.38) | MAOAMAOBCA1CA2ABCG2 | |
| SCHEMBL12540914 | 0.68 | SIGMAR1 (0.55) | SIGMAR1NISCHMAOAMAOB | |
| SCHEMBL15069597 | 0.68 | SIGMAR1 (0.55) | SIGMAR1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359290-B1 | AROMATIC DIOLS | GLAXO GROUP LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |
| EP-0359290-A1 | Aromatic diols | GLAXO GROUP LIMITED (GB) | 1990-03-21 | — | — | EP | disclosed |