SCHEMBL28242590

SCHEMBL28242590

FC1(F)OCc2ccccc2O1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.43
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
OXTR P30559 1/20 0.35
NISCH Q9Y2I1 1/20 0.33
GPR3 P46089 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.31
ITGB2 P05107 1/20 0.31
ICAM1 P05362 1/20 0.31
ITGAL P20701 1/20 0.31
HSD17B3 P37058 1/20 0.31
DRD2 P14416 1/20 0.30
HTR2A P28223 1/20 0.30
KMT2A Q03164 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30005029 0.76 SIGMAR1 (0.44) SIGMAR1MAOAMAOBNISCHHSD17B3
SCHEMBL9530682 0.75 SIGMAR1 (0.43) SIGMAR1MAOAMAOBOXTRNISCH
SCHEMBL4854732 0.75 SIGMAR1 (0.43) SIGMAR1MAOAMAOBNISCHHSD17B3
SCHEMBL29625352 0.75 SIGMAR1 (0.43) SIGMAR1MAOAMAOBNISCHHSD17B3
SCHEMBL31325075 0.75 SIGMAR1 (0.46) SIGMAR1MAOAMAOBOXTRNISCH
SCHEMBL10965410 0.73 SIGMAR1 (0.45) SIGMAR1MAOAMAOBOXTRNISCH
SCHEMBL200514 0.71 GPR3 (0.45) MAOAMAOBGPR3ABCG2ITGB2
SCHEMBL7171771 0.71 TRPM8 (0.33) SIGMAR1
SCHEMBL6006049 0.71 PIM1 (0.33)
SCHEMBL3122824 0.70 MAOA (0.39) SIGMAR1MAOAMAOBOXTRNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024032715-A1 HYDRAZIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳微芯生物科技股份有限公司 2024-02-15 WO disclosed
CN-108463463-A Compound, preparation method and its medical usage of antagonism A3 adenosine receptors 韩德株式会社 2018-08-28 CN disclosed