Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531822 | 0.86 | MAOB (0.43) | ALDH1A1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9533182 | 0.85 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9531990 | 0.84 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9533339 | 0.83 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9531752 | 0.81 | MAPT (0.48) | ALDH1A1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9631291 | 0.80 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9532298 | 0.79 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL9632290 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL9533164 | 0.77 | TLR3 (0.48) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL9533103 | 0.77 | KMT2A (0.47) | ALDH1A1NPC1RAB9AMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |