Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530858 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL9532214 | 0.84 | MAOB (0.43) | ALDH1A1NPC1RAB9AMAOBKDM4E | |
| SCHEMBL9533182 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL9533339 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL9531752 | 0.80 | MAPT (0.48) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL9631291 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL9533103 | 0.78 | KMT2A (0.47) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL9534457 | 0.77 | MAPT (0.45) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL25082424 | 0.77 | ATM (0.44) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL6601579 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |