Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526286 | 0.94 | B3GAT3 (0.33) | KDM2BMTNR1AMTNR1B | |
| SCHEMBL9527493 | 0.86 | B3GAT3 (0.33) | KDM2B | |
| SCHEMBL9527486 | 0.84 | B3GAT3 (0.35) | MTNR1AMTNR1B | |
| SCHEMBL9527773 | 0.83 | B3GAT3 (0.35) | KDM2B | |
| SCHEMBL9526830 | 0.82 | NPC1 (0.35) | NPC1RAB9AKDM2BMTNR1AMTNR1B | |
| SCHEMBL9526625 | 0.81 | B3GAT3 (0.33) | — | |
| SCHEMBL9526603 | 0.79 | CCR2 (0.34) | — | |
| SCHEMBL9526819 | 0.77 | CCR2 (0.33) | KDM2B | |
| SCHEMBL9530873 | 0.77 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9527072 | 0.76 | B3GAT3 (0.34) | KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |