Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527665 | 0.93 | B3GAT3 (0.35) | RAB9AROCK2MTNR1AMTNR1BTRPV1 | |
| SCHEMBL9527712 | 0.92 | NPC1 (0.35) | NPC1RAB9AKDM2BROCK2TSHR | |
| SCHEMBL9526764 | 0.91 | NPC1 (0.37) | NPC1RAB9AROCK2MTNR1AMTNR1B | |
| SCHEMBL9526771 | 0.86 | NPC1 (0.34) | NPC1RAB9AKDM2BROCK2TSHR | |
| SCHEMBL9527280 | 0.86 | B3GAT3 (0.34) | RAB9AKDM2B | |
| SCHEMBL9528145 | 0.85 | KDM2B (0.35) | NPC1RAB9AKDM2BTSHR | |
| SCHEMBL9528457 | 0.85 | MEN1 (0.40) | — | |
| SCHEMBL9526686 | 0.84 | NPC1 (0.36) | NPC1RAB9AROCK2TSHR | |
| SCHEMBL9526859 | 0.83 | B3GAT3 (0.36) | RAB9AROCK2MTNR1AMTNR1BTRPV1 | |
| SCHEMBL9530877 | 0.82 | NPC1 (0.32) | NPC1RAB9AKDM2BMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0337767-A1 | Cyclic amides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |