Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.55 |
| ▸ | DRD2 | P14416 | 6/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674604 | 0.85 | HTR1A (0.55) | HTR1ADRD2DRD3 | |
| SCHEMBL7908075 | 0.84 | HTR1A (0.48) | HTR1ADRD2DRD3 | |
| SCHEMBL4062423 | 0.81 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL599870 | 0.81 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL9674292 | 0.74 | HTR1A (0.53) | HTR1ADRD2DRD3 | |
| SCHEMBL7905525 | 0.72 | HTR1A (0.47) | HTR1ADRD2DRD3 | |
| SCHEMBL7904363 | 0.72 | HTR1A (0.42) | HTR1ADRD2PSMB8 | |
| SCHEMBL7344870 | 0.71 | HTR1A (1.00) | HTR1ADRD2DRD3 | |
| SCHEMBL9526261 | 0.70 | HTR1A (0.54) | HTR1ADRD2DRD3 | |
| SCHEMBL7908113 | 0.69 | HTR1A (0.49) | HTR1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384522-B1 | Antiviral tetrahydroimidazo[1,4]benzodiazepin-2-thiones | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-13 | — | — | EP | claimed |
| JP-2270876-A | — | — | None | — | — | JP | disclosed |
| JP-H02270876-A | ANTIVIRAL TETRAHYDROIMIDAZO(1,4)BENZODIAZEPIN-2-THIONE | JANSSEN PHARMACEUT NV | 1990-11-05 | — | — | JP | disclosed |