Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.55 |
| ▸ | DRD2 | P14416 | 6/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674292 | 0.86 | HTR1A (0.53) | HTR1ADRD2DRD3 | |
| SCHEMBL7905525 | 0.86 | HTR1A (0.47) | HTR1ADRD2DRD3 | |
| SCHEMBL9531050 | 0.85 | HTR1A (0.55) | HTR1ADRD2DRD3 | |
| SCHEMBL9526261 | 0.84 | HTR1A (0.54) | HTR1ADRD2DRD3 | |
| SCHEMBL7896210 | 0.83 | HTR1A (0.55) | HTR1ADRD2DRD3 | |
| SCHEMBL6363122 | 0.83 | HTR1A (0.55) | HTR1ADRD2DRD3 | |
| SCHEMBL7908113 | 0.83 | HTR1A (0.49) | HTR1ADRD2DRD3 | |
| SCHEMBL9676278 | 0.82 | HTR1A (0.51) | HTR1ADRD2DRD3 | |
| SCHEMBL9676122 | 0.82 | HTR1A (0.51) | HTR1ADRD2DRD3 | |
| SCHEMBL9676250 | 0.81 | HTR1A (0.47) | HTR1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336466-B1 | ANTIVIRAL TETRAHYDROIMIDAZO (1,4) BENZODIAZEPIN-2-ONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-30 | — | — | EP | claimed |