Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9874843 | 0.85 | SIGMAR1 (0.45) | NPC1RAB9ASIGMAR1HTR2C | |
| SCHEMBL9879898 | 0.78 | SIGMAR1 (0.44) | SIGMAR1LMNA | |
| SCHEMBL6648539 | 0.78 | SIGMAR1 (0.37) | SIGMAR1HTR2C | |
| Hydrochloric Acid SCHEMBL9472430 | 0.75 | SIGMAR1 (0.40) | NPC1RAB9ASIGMAR1HTR2C | |
| SCHEMBL9874667 | 0.74 | SIGMAR1 (0.46) | NPC1RAB9ASIGMAR1HTR2CLMNA | |
| SCHEMBL4790395 | 0.72 | SIGMAR1 (0.50) | SIGMAR1HTR2CSLC6A3 | |
| SCHEMBL4688277 | 0.71 | RARB (0.44) | NPC1RAB9A | |
| SCHEMBL9171148 | 0.71 | SIGMAR1 (0.41) | SIGMAR1HTR2CLMNA | |
| SCHEMBL9172360 | 0.71 | GRIN2B (0.34) | SIGMAR1HTR2C | |
| Hydrochloric Acid SCHEMBL8970717 | 0.70 | F2 (0.39) | LMNAUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |