Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9874843 | 0.83 | SIGMAR1 (0.45) | SIGMAR1KMT2AMEN1 | |
| SCHEMBL9879899 | 0.71 | SIGMAR1 (0.81) | SIGMAR1ALDH1A1HTTTAAR1 | |
| SCHEMBL9828028 | 0.66 | MEN1 (0.62) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL9284598 | 0.64 | ALDH1A1 (0.55) | MAPTLMNAL3MBTL1TUBB4ATUBB | |
| SCHEMBL9532694 | 0.63 | SLC6A2 (0.37) | SIGMAR1LMNA | |
| SCHEMBL2925144 | 0.63 | CCNT1 (0.41) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2925142 | 0.63 | CCNT1 (0.41) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3137049 | 0.63 | THRA (0.56) | MAPTLMNATHRBL3MBTL1TUBB4A | |
| SCHEMBL10789209 | 0.63 | ALDH1A1 (0.57) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7837299 | 0.63 | ALDH1A1 (0.61) | LMNAL3MBTL1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008200-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AS ACTIVE AGENTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | claimed |