Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9874843 | 0.80 | SIGMAR1 (0.45) | SIGMAR1KMT2ANPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL9472430 | 0.78 | SIGMAR1 (0.40) | SIGMAR1MAPTL3MBTL1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8970717 | 0.75 | F2 (0.39) | MAPTALDH1A1LMNASMN1; SMN2MMP2 | |
| SCHEMBL9531072 | 0.74 | NPC1 (0.47) | SIGMAR1NPC1RAB9AHTR2CLMNA | |
| SCHEMBL10372460 | 0.72 | CNR1 (0.37) | CNR1 | |
| SCHEMBL252506 | 0.70 | ALDH1A1 (0.51) | MAPTL3MBTL1ALDH1A1KMT2ANPC1 | |
| SCHEMBL6845223 | 0.70 | ALDH1A1 (0.51) | MAPTL3MBTL1ALDH1A1KMT2ANPC1 | |
| SCHEMBL9879898 | 0.69 | SIGMAR1 (0.44) | SIGMAR1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8507430 | 0.69 | HTR2C (0.41) | SIGMAR1HTR2CHSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL10373507 | 0.69 | CNR1 (0.33) | SIGMAR1L3MBTL1ALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008200-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AS ACTIVE AGENTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | claimed |