Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.59 |
| ▸ | FNTB | P49356 | 4/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748237 | 0.84 | KDM4E (0.46) | FNTAFNTBNOTUMALDH1A1KDM4E | |
| SCHEMBL28325980 | 0.80 | MYC (0.49) | FNTAFNTBNOTUMALDH1A1KDM4E | |
| SCHEMBL9531095 | 0.79 | FNTA (0.69) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL10797200 | 0.79 | FNTA (0.59) | FNTAFNTBALDH1A1KDM4EGLA | |
| SCHEMBL9531986 | 0.79 | FNTA (0.60) | FNTAFNTBALDH1A1KDM4EGLA | |
| SCHEMBL27767830 | 0.79 | FNTA (0.60) | FNTAFNTBALDH1A1KDM4EGLA | |
| SCHEMBL4705312 | 0.78 | FNTA (0.55) | FNTAFNTBALDH1A1KDM4EGLA | |
| SCHEMBL16261172 | 0.78 | SSTR4 (0.46) | FNTAFNTBALDH1A1KDM4EGLA | |
| SCHEMBL27843160 | 0.77 | FNTA (0.58) | FNTAFNTBALDH1A1KDM4EGLA | |
| SCHEMBL16261173 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289170-B1 | AZABICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1993-06-23 | — | — | EP | disclosed |
| US-4882327-A | NERVOUS SYSTEM DISORDERS | BEECHAM GROUP P.L.C. (GB) | 1989-11-21 | — | — | US | disclosed |
| EP-0289170-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-11-02 | — | — | EP | disclosed |