Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206816 | 0.78 | GID4 (0.43) | TAAR1OPRD1OPRM1 | |
| SCHEMBL9209208 | 0.77 | GID4 (0.42) | TAAR1OPRD1OPRM1 | |
| SCHEMBL9531248 | 0.73 | TAAR1 (0.52) | TAAR1 | |
| SCHEMBL3453173 | 0.73 | OPRM1 (0.56) | OPRM1 | |
| SCHEMBL3312684 | 0.73 | KMT2A (0.37) | TAAR1 | |
| SCHEMBL4709300 | 0.72 | SLC22A1 (0.59) | — | |
| SCHEMBL329925 | 0.72 | OPRM1 (0.57) | OPRM1 | |
| SCHEMBL330238 | 0.72 | OPRM1 (0.57) | OPRM1 | |
| SCHEMBL329828 | 0.72 | OPRM1 (0.57) | OPRM1 | |
| SCHEMBL14903796 | 0.72 | TAAR1 (0.56) | TAAR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575362-A1 | TETRAHYDROTHIENO(2,3-c)PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATION | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992015592-A1 | TETRAHYDROTHIENO(2,3-c)PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATION | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1992-09-17 | — | — | WO | disclosed |