Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906118 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL9529749 | 0.75 | GRM5 (0.33) | TGFBR1GRIN2B | |
| SCHEMBL9531665 | 0.73 | KIF11 (0.39) | TGFBR1KIF11PTGS2SLC9A1PTGS1 | |
| SCHEMBL2751962 | 0.68 | TGFBR1 (0.33) | TGFBR1KIF11PTPN1GRIN2B | |
| SCHEMBL15814002 | 0.66 | F2RL3 (0.42) | — | |
| SCHEMBL3488246 | 0.66 | KDM4E (0.43) | — | |
| SCHEMBL2563135 | 0.65 | ALDH1A1 (0.35) | KIF11PTGS2 | |
| SCHEMBL2555113 | 0.65 | CYP1A2 (0.37) | KIF11SCN9A | |
| SCHEMBL16986456 | 0.65 | PTPN1 (0.33) | TGFBR1PTPN1GRIN2B | |
| SCHEMBL22659043 | 0.65 | AGPAT2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |