Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531370 | 1.00 | ALDH1A1 (0.35) | ALDH1A1GAAKDM4ENOS1NOS3 | |
| SCHEMBL9423996 | 0.86 | GAA (0.34) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL9423994 | 0.86 | GAA (0.34) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL27293731 | 0.82 | POLB (0.39) | ALDH1A1GAAKDM4ENOS1NOS3 | |
| SCHEMBL9532357 | 0.82 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL9533902 | 0.81 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4EKMT2AMEN1 | |
| SCHEMBL9533260 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GAAKMT2AMEN1POLB | |
| SCHEMBL9533258 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GAAKMT2AMEN1POLB | |
| SCHEMBL9059748 | 0.73 | GAA (0.36) | ALDH1A1GAAKDM4ENOS1NOS3 | |
| SCHEMBL9059752 | 0.73 | GAA (0.36) | ALDH1A1GAAKDM4ENOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560794-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. | IAF BIOCHEM INT (CA) | 1993-09-22 | — | — | EP | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |