Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533258 | 1.00 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL9424006 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL9424008 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL9530216 | 0.84 | GAA (0.36) | ALDH1A1KMT2AL3MBTL1MEN1ALOX15 | |
| SCHEMBL9530210 | 0.84 | GRIN2D (0.32) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9532357 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL9424153 | 0.83 | ALOX15 (0.39) | ALDH1A1KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL9424151 | 0.83 | ALOX15 (0.39) | ALDH1A1KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL9533902 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL9424265 | 0.82 | LMNA (0.42) | ALDH1A1KMT2AL3MBTL1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |