Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533644 | 0.90 | HTR2C (0.40) | HTR2CHTR2BATMMEN1TP53 | |
| SCHEMBL1707125 | 0.71 | MEN1 (0.40) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL10192226 | 0.69 | KDM4E (0.41) | ALDH1A1KDM4EHTTATMMEN1 | |
| SCHEMBL7417868 | 0.69 | KDM4E (0.41) | ALDH1A1KDM4EHTTATMMEN1 | |
| SCHEMBL3560241 | 0.67 | SIGMAR1 (0.57) | HTR2CTSHR | |
| SCHEMBL7858958 | 0.67 | SIGMAR1 (0.41) | ALDH1A1KDM4EHTTATMMEN1 | |
| SCHEMBL9532960 | 0.67 | TSHR (0.37) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL1115308 | 0.67 | HTR2C (0.70) | HTR2CHTR2BALDH1A1 | |
| SCHEMBL2113696 | 0.66 | ALDH1A1 (0.38) | ALDH1A1KDM4EHTTATMMEN1 | |
| SCHEMBL11005301 | 0.65 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |