Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531366 | 0.90 | HTR2C (0.37) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL1707125 | 0.75 | MEN1 (0.40) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL9532960 | 0.71 | TSHR (0.37) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL9531727 | 0.68 | MEN1 (0.35) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL9531180 | 0.67 | MEN1 (0.34) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL15388704 | 0.65 | ABCG2 (0.44) | MEN1MAPTKMT2ASIGMAR1ABCG2 | |
| SCHEMBL22032186 | 0.65 | SIGMAR1 (0.44) | HTR2CMEN1TSHRKMT2AOPRD1 | |
| SCHEMBL30726648 | 0.63 | HTR2C (0.37) | HTR2CHTR2BMEN1TP53MAPT | |
| SCHEMBL13209512 | 0.61 | ALOX5 (0.40) | HTR2CHTR2BMAPTTSHRKMT2A | |
| SCHEMBL31318556 | 0.61 | ALOX5 (0.40) | HTR2CHTR2BMAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |