Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531990 | 0.84 | ALDH1A1 (0.52) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9531822 | 0.83 | MAOB (0.43) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL10656598 | 0.82 | MAOB (0.36) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL25082424 | 0.80 | ATM (0.44) | MAOBKDM4EALDH1A1ATMSIGMAR1 | |
| SCHEMBL9531668 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL9535699 | 0.77 | MEN1 (0.57) | ALDH1A1HPGDHSD17B10FFAR1 | |
| SCHEMBL9531218 | 0.76 | TSHR (0.44) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9534822 | 0.76 | ALDH1A1 (0.41) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9533035 | 0.75 | ESR1 (0.40) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9533181 | 0.74 | KDM4E (0.40) | MAOBKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |