Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531317 | 0.90 | AGTR1 (0.39) | PPARGAGTR1AGTR2 | |
| SCHEMBL9531505 | 0.89 | FFAR1 (0.40) | PPARGAGTR1AGTR2 | |
| SCHEMBL9530983 | 0.88 | PPARG (0.40) | PPARGAGTR1AGTR2 | |
| SCHEMBL9530765 | 0.86 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9532830 | 0.81 | AGTR1 (0.35) | PPARGAGTR1AGTR2 | |
| SCHEMBL9533202 | 0.81 | CD274 (0.38) | PPARGAGTR1AGTR2 | |
| SCHEMBL9531282 | 0.81 | PPARG (0.37) | PPARGAGTR1AGTR2 | |
| SCHEMBL8332201 | 0.79 | AGTR1 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL9531010 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9530817 | 0.78 | FFAR1 (0.36) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515548-A4 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0515548-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |