Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528147 | 0.88 | TBXAS1 (0.55) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9529775 | 0.88 | TBXAS1 (0.50) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9529151 | 0.85 | TBXAS1 (0.60) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9527829 | 0.83 | MAPK1 (0.55) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9529952 | 0.81 | TBXAS1 (0.52) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9532138 | 0.81 | TBXAS1 (0.55) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9528581 | 0.81 | TBXAS1 (0.59) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9528365 | 0.80 | TBXAS1 (0.58) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9527952 | 0.80 | ALDH1A1 (0.49) | TBXAS1TBXA2RALDH1A1MAPTMEN1 | |
| SCHEMBL9532300 | 0.79 | TBXAS1 (0.57) | TBXAS1TBXA2RALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |