Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529674 | 0.88 | TBXAS1 (0.48) | TBXAS1TBXA2RMAPTKDM4EGAA | |
| SCHEMBL9529151 | 0.83 | TBXAS1 (0.60) | TBXAS1TBXA2RMAPTALDH1A1MEN1 | |
| SCHEMBL9529774 | 0.81 | ALDH1A1 (0.50) | TBXAS1TBXA2RKDM4EALDH1A1MEN1 | |
| SCHEMBL9532150 | 0.81 | TBXAS1 (0.55) | TBXAS1TBXA2RMAPTALDH1A1MEN1 | |
| SCHEMBL9528581 | 0.81 | TBXAS1 (0.59) | TBXAS1TBXA2RMAPTKDM4EALDH1A1 | |
| SCHEMBL9528365 | 0.80 | TBXAS1 (0.58) | TBXAS1TBXA2RMAPTKDM4EALDH1A1 | |
| SCHEMBL9532300 | 0.79 | TBXAS1 (0.57) | TBXAS1TBXA2RKDM4EALDH1A1MEN1 | |
| SCHEMBL9528147 | 0.76 | TBXAS1 (0.55) | TBXAS1TBXA2RMAPTALDH1A1MEN1 | |
| SCHEMBL9527676 | 0.76 | TBXAS1 (0.63) | TBXAS1TBXA2RKDM4EALDH1A1KMT2A | |
| SCHEMBL9529664 | 0.76 | TBXAS1 (0.63) | TBXAS1TBXA2RKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |