Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.44 |
| ▸ | RXRB | P28702 | 5/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530752 | 0.82 | RXRA (0.45) | RXRARXRBNR1H4NR4A2NPC1 | |
| SCHEMBL9531402 | 0.75 | RXRA (0.43) | RXRARXRBNR1H4NR4A2NPC1 | |
| SCHEMBL9755563 | 0.72 | AGTR1 (0.52) | RXRARXRBNR4A2 | |
| SCHEMBL1123143 | 0.70 | RXRA (0.72) | RXRARXRBNR1H4NR4A2NPC1 | |
| SCHEMBL10789890 | 0.67 | RXRA (0.70) | RXRARXRBNR4A2NPC1POLB | |
| SCHEMBL11358158 | 0.66 | RARB (0.68) | RXRARXRBNR4A2NPC1POLB | |
| SCHEMBL18521456 | 0.66 | RARB (0.68) | RXRARXRBNR4A2NPC1POLB | |
| SCHEMBL18521452 | 0.66 | RARB (0.68) | RXRARXRBNR4A2NPC1POLB | |
| SCHEMBL9372929 | 0.66 | RXRA (0.77) | RXRARXRBNR4A2NPC1POLB | |
| SCHEMBL17112801 | 0.66 | RXRA (0.77) | RXRARXRBNR4A2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515548-A4 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0515548-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |