SCHEMBL9532309

SCHEMBL9532309

CCCCCCCCCCCCCCCCCNC(=O)OC[C@H](COCOCCOC)Oc1ccon1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
PTAFR P25105 1/20 0.40
MTOR P42345 1/20 0.40
BLM P54132 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
TLR2 O60603 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9532304 1.00 GMNN (0.40) GMNNUSP2LMNAPTAFRMTOR
SCHEMBL9528828 0.84 ATM (0.41)
SCHEMBL9528831 0.84 ATM (0.41)
SCHEMBL9798998 0.82 GMNN (0.41) GMNNUSP2LMNAPTAFRMTOR
SCHEMBL9798991 0.82 GMNN (0.41) GMNNUSP2LMNAPTAFRMTOR
SCHEMBL9532112 0.79 ATM (0.42)
SCHEMBL9530013 0.79 SMN1; SMN2 (0.50) GMNNUSP2LMNAPTAFRMTOR
SCHEMBL9530021 0.79 SMN1; SMN2 (0.50) GMNNUSP2LMNAPTAFRMTOR
SCHEMBL9531777 0.79 PLA2G2A (0.39)
SCHEMBL9529278 0.78 HPGD (0.42) TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238202-B1 GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE Sankyo Company Limited (JP) 1993-04-28 EP disclosed
US-5068340-A Antagonist of platelet activating factor for treatment of asthma, inflammation or shock SANKYO COMPANY, LIMITED (JP) 1991-11-26 US disclosed
EP-0238202-A2 Glycerol derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1987-09-23 EP disclosed