Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528828 | 0.83 | ATM (0.41) | FAAH | |
| SCHEMBL9528831 | 0.83 | ATM (0.41) | FAAH | |
| SCHEMBL9529273 | 0.83 | HPGD (0.42) | FAAH | |
| SCHEMBL9529278 | 0.83 | HPGD (0.42) | FAAH | |
| SCHEMBL9529285 | 0.83 | HPGD (0.42) | FAAH | |
| SCHEMBL9798948 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5FAAH | |
| SCHEMBL9798355 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5FAAH | |
| SCHEMBL9798365 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5FAAH | |
| SCHEMBL9799022 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5FAAH | |
| SCHEMBL9669469 | 0.80 | HDAC6 (0.41) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |