SCHEMBL9528831

SCHEMBL9528831

CCCCCCCCCCCCCCCCCNC(=O)OC[C@H](CO)Oc1ccon1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
ALDH1A1 P00352 1/20 0.41
FAAH O00519 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9528828 1.00 ATM (0.41) ATMALDH1A1FAAH
SCHEMBL9532112 0.86 ATM (0.42) ATMALDH1A1FAAH
SCHEMBL9532304 0.84 GMNN (0.40)
SCHEMBL9532309 0.84 GMNN (0.40)
SCHEMBL9531777 0.83 PLA2G2A (0.39) FAAH
SCHEMBL9529278 0.83 HPGD (0.42) FAAH
SCHEMBL9798991 0.83 GMNN (0.41)
SCHEMBL9529285 0.83 HPGD (0.42) FAAH
SCHEMBL9798998 0.83 GMNN (0.41)
SCHEMBL9529273 0.83 HPGD (0.42) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238202-B1 GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE Sankyo Company Limited (JP) 1993-04-28 EP disclosed
US-5068340-A Antagonist of platelet activating factor for treatment of asthma, inflammation or shock SANKYO COMPANY, LIMITED (JP) 1991-11-26 US disclosed
EP-0238202-A2 Glycerol derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1987-09-23 EP disclosed