Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853651 | 0.89 | KDM4E (0.60) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD | |
| SCHEMBL852375 | 0.87 | KDM4E (0.67) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD | |
| SCHEMBL9529563 | 0.83 | CYSLTR1 (0.63) | PPARGPPARDPPARA | |
| SCHEMBL22074515 | 0.81 | S1PR1 (0.39) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD | |
| SCHEMBL5097564 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD | |
| SCHEMBL853659 | 0.80 | BACE1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10PDGFRB | |
| SCHEMBL12598336 | 0.80 | MAPT (0.58) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD | |
| SCHEMBL853596 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD | |
| SCHEMBL710398 | 0.80 | KDM4E (0.73) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD | |
| SCHEMBL7838194 | 0.80 | TRPM8 (0.67) | ALDH1A1KDM4ECYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544821-A1 | INDOLE DERIVATIVES AS ANTIALLERGY AND ANTIINFLAMMATORY AGENTS. | PFIZER (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992006088-A1 | INDOLE DERIVATIVES AS ANTIALLERGY AND ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1992-04-16 | — | — | WO | disclosed |