Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532138 | 0.87 | TBXAS1 (0.55) | TBXAS1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL9529178 | 0.86 | ALDH1A1 (0.60) | TBXAS1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9528581 | 0.86 | TBXAS1 (0.59) | TBXAS1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8804598 | 0.85 | TBXAS1 (0.54) | TBXAS1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8803341 | 0.85 | TBXAS1 (0.54) | TBXAS1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9528365 | 0.84 | TBXAS1 (0.58) | TBXAS1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9527829 | 0.84 | MAPK1 (0.55) | TBXAS1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9532300 | 0.84 | TBXAS1 (0.57) | TBXAS1MEN1KMT2AALDH1A1TBXA2R | |
| SCHEMBL9532489 | 0.83 | CYP11B1 (0.52) | ABCB1TBXAS1CYP11B1CYP11B2KMT2A | |
| SCHEMBL9529072 | 0.83 | CYP11B1 (0.54) | ABCB1TBXAS1CYP11B1CYP11B2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |