Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529072 | 0.92 | CYP11B1 (0.54) | CYP11B1CYP11B2LRRK2TBXAS1SMN1; SMN2 | |
| SCHEMBL9527952 | 0.84 | ALDH1A1 (0.49) | CYP11B1CYP11B2TBXAS1KMT2APOLB | |
| SCHEMBL9532138 | 0.84 | TBXAS1 (0.55) | CYP11B1CYP11B2TBXAS1KMT2AKDM4E | |
| SCHEMBL9529775 | 0.83 | TBXAS1 (0.50) | CYP11B1CYP11B2TBXAS1SMN1; SMN2TSHR | |
| SCHEMBL9532347 | 0.83 | ABCB1 (0.53) | CYP11B1CYP11B2TBXAS1SMN1; SMN2TSHR | |
| SCHEMBL9527829 | 0.81 | MAPK1 (0.55) | TBXAS1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL9532300 | 0.81 | TBXAS1 (0.57) | TBXAS1SMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9528581 | 0.80 | TBXAS1 (0.59) | TBXAS1SMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9528781 | 0.79 | MAPK1 (0.58) | TBXAS1SMN1; SMN2KMT2APOLBKDM4E | |
| SCHEMBL9531922 | 0.79 | TBXAS1 (0.52) | TBXAS1SMN1; SMN2KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |