Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439073 | 0.85 | HPGD (0.41) | HPGDEPHX1KMT2AEPHX2LMNA | |
| SCHEMBL791953 | 0.80 | EPHX1 (0.41) | HPGDEPHX1KMT2AEPHX2LMNA | |
| SCHEMBL787945 | 0.80 | CYP1A2 (0.48) | HPGDEPHX1KMT2AEPHX2 | |
| SCHEMBL4642050 | 0.80 | HPGD (0.37) | HPGDEPHX1KMT2AEPHX2LMNA | |
| SCHEMBL1148328 | 0.78 | EPHX1 (0.54) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| SCHEMBL7945281 | 0.78 | EPHX1 (0.54) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| SCHEMBL13485707 | 0.78 | CYP1A2 (0.45) | HPGDEPHX1KMT2A | |
| SCHEMBL19508699 | 0.77 | NAAA (0.53) | EPHX1KMT2AEPHX2 | |
| SCHEMBL2990381 | 0.77 | NAAA (0.53) | EPHX1KMT2AEPHX2 | |
| SCHEMBL11625205 | 0.77 | NAAA (0.53) | EPHX1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555331-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1993-08-18 | — | — | EP | claimed |