SCHEMBL95326

SCHEMBL95326

C=C(C)C(=O)OCC(=O)NN1CCN(CC)C1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
TSHR P16473 3/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10856249 0.80 THRB (0.35) THRBTSHR
SCHEMBL94348 0.79 GAA (0.33) GAAL3MBTL1
SCHEMBL9064540 0.76 THRB (0.34) THRBTSHRGAAALDH1A1
SCHEMBL3219649 0.70 THRB (0.32) THRBTSHRGAAALDH1A1L3MBTL1
SCHEMBL974246 0.70 FGFR4 (0.35) TSHRGAAALDH1A1L3MBTL1
SCHEMBL9470924 0.69 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL4185493 0.69 TSHR (0.42) THRBTSHRALDH1A1
SCHEMBL4188784 0.66 THRB (0.44) THRBTSHRALDH1A1
SCHEMBL18656239 0.65 THRB (0.46) THRBTSHRALDH1A1L3MBTL1
SCHEMBL18317189 0.64 THRB (0.34) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7241834-B2 Forming an aqueous coating comprising an aqueous acrylic emulsion polymer, applying coating to a substrate; and drying, or allowing to dry applied coating ROHM AND HAAS COMPANY (US) 2007-07-10 US claimed
EP-2327729-B1 Polymer composition and monomer composition for preparing thereof ROHM & HAAS (US) 2017-11-29 EP disclosed
EP-2426155-B2 Multistage emulsion polymer and improved pigment efficiency ROHM & HAAS (US) 2017-06-28 EP disclosed
US-9447215-B2 Multistage emulsion polymer and improved pigment efficiency ROHM AND HAAS COMPANY (US) 2016-09-20 US disclosed
US-8710133-B2 Stable aqueous composite compositions ROHM AND HAAS COMPANY (US) 2014-04-29 US disclosed
EP-2426155-B1 Multistage emulsion polymer and improved pigment efficiency ROHM & HAAS (US) 2013-10-16 EP disclosed
EP-1344786-B1 Polymer composition and monomer composition for preparing thereof ROHM & HAAS (US) 2013-07-24 EP disclosed
US-20120058278-A1 STABLE AQUEOUS COMPOSITE COMPOSITIONS ROHM AND HAAS COMPANY 2012-03-08 US disclosed
US-20120058277-A1 MULTISTAGE EMULSION POLYMER AND IMPROVED PIGMENT EFFICIENCY ROHM AND HAAS COMPANY 2012-03-08 US disclosed
EP-2426155-A1 Multistage emulsion polymer and improved pigment efficiency Rohm and Haas Company (US) 2012-03-07 EP disclosed
EP-1352924-A1 Aqueous polymer blend composition ROHM AND HAAS COMPANY (US) 2003-10-15 EP disclosed
EP-1344786-A2 Polymer composition and monomer composition for preparing thereof ROHM AND HAAS COMPANY (US) 2003-09-17 EP disclosed
US-20030059599-A1 Coating and coating composition ROHM AND HAAS COMPANY, A CORP. OF DELAWARE 2003-03-27 US disclosed
US-6524656-B2 Forming aqueous coating using polymer formed by free radical polymerization of ethylenically unsaturated nonionic acrylic monomer, ethylenically unsaturated aldehyde reactive group containing monomer, ethylenically unsaturated acid monomer ROHM AND HAAS COMPANY 2003-02-25 US disclosed
US-20020160118-A1 Coating method ROHM AND HAAS COMPANY 2002-10-31 US disclosed
EP-1245587-A1 Improved coating and coating composition ROHM AND HAAS COMPANY (US) 2002-10-02 EP disclosed
EP-1234840-A2 Coating method, method for improving the scrub resistance and the adhesion to a substrate, lowering the minimum film formation temperature ROHM AND HAAS COMPANY (US) 2002-08-28 EP disclosed
US-20020090459-A1 Aqueous acrylic emulsion polymer composition ROHM AND HAAS COMPANY 2002-07-11 US disclosed
US-4254003-A CONTAINING POLAR GROUPS FOR PAINTS DULUX AUSTRALIA LTD. (AU) 1981-03-03 US disclosed
US-4248754-A WATERPROOF PAINTS DULUX AUSTRALIA LTD (AU) 1981-02-03 US disclosed