Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532844 | 0.87 | SIGMAR1 (0.34) | SIGMAR1HTR2C | |
| SCHEMBL9175105 | 0.72 | CYP1A2 (0.38) | SLC6A2SLC6A4SLC6A3SIGMAR1HTR2C | |
| SCHEMBL9171872 | 0.72 | GRIN1 (0.36) | SIGMAR1HTR2C | |
| SCHEMBL4790395 | 0.71 | SIGMAR1 (0.50) | SLC6A2SLC6A4SLC6A3SIGMAR1HTR2C | |
| SCHEMBL9531072 | 0.70 | NPC1 (0.47) | SLC6A3SIGMAR1HTR2CLMNA | |
| Hydrochloric Acid SCHEMBL8970717 | 0.69 | F2 (0.39) | LMNA | |
| SCHEMBL6648539 | 0.67 | SIGMAR1 (0.37) | SIGMAR1HTR2C | |
| SCHEMBL7360100 | 0.67 | SIGMAR1 (0.49) | SLC6A2SLC6A4SLC6A3SIGMAR1HTR2C | |
| Hydrochloric Acid SCHEMBL9874843 | 0.66 | SIGMAR1 (0.45) | SIGMAR1HTR2C | |
| SCHEMBL9171148 | 0.65 | SIGMAR1 (0.41) | SIGMAR1HTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |