Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1796749 | 0.92 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL8289135 | 0.92 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL1796753 | 0.92 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL17257187 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL9532057 | 0.83 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL9530015 | 0.83 | KDM4E (0.57) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL9529568 | 0.78 | KDM4E (0.51) | NPC1RAB9AKMT2APKMMITF | |
| SCHEMBL9528646 | 0.76 | CES2 (0.50) | NPC1RAB9ALMNAL3MBTL1KMT2A | |
| SCHEMBL9532752 | 0.75 | RAB9A (0.47) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10452205 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143055-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | Bridgestone Corporation (JP) | 2017-03-22 | — | — | EP | claimed |
| WO-2015175280-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | WO | claimed |
| JP-53116378-A | — | — | None | — | — | JP | disclosed |
| EP-3143055-B1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORP (JP) | 2019-09-04 | — | — | EP | disclosed |
| CN-100482646-C | N- [ phenyl (piperidin-2-yl) methyl ] benzamide derivatives, their preparation and their use in therapy | SANOFI AVENTIS (FR) | 2009-04-29 | — | — | CN | disclosed |
| CN-1662497-A | N- [ phenyl (piperidin-2-yl) methyl ] benzamide derivatives, their preparation and their use in therapy | SANOFI AVENTIS (FR) | 2005-08-31 | — | — | CN | disclosed |
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| JP-S53116378-A | PYRIDYLKETONEOXIMEBENZYLETHERS PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THE SAME | SUMITOMO CHEM CO LTD | 1978-10-11 | — | — | JP | disclosed |