Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124946 | 0.84 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL17210661 | 0.80 | MEN1 (0.39) | ALDH1A1TSHRCYP3A4TDP1NR1H2 | |
| SCHEMBL15984367 | 0.79 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL1793818 | 0.78 | NR1H2 (0.48) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL12374438 | 0.77 | SLC2A1 (0.58) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL31493129 | 0.76 | NR1H2 (0.46) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL6278267 | 0.74 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL4400877 | 0.74 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL5494992 | 0.74 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL11476112 | 0.72 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250193-B1 | Photoreactive lenses | MARCONI GEC LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| EP-0250193-A2 | Photoreactive lenses | GEC-MARCONI LIMITED (GB) | 1987-12-23 | — | — | EP | disclosed |