Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793818 | 0.93 | NR1H2 (0.48) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL31493129 | 0.91 | NR1H2 (0.46) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL9533063 | 0.84 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL19140594 | 0.81 | CNR2 (0.42) | ALDH1A1TSHRMAPK1NR1H2NR1H3 | |
| SCHEMBL1409015 | 0.79 | SLC2A1 (0.59) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL25954205 | 0.79 | SLC2A1 (0.59) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL12374438 | 0.78 | SLC2A1 (0.58) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL15984367 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 | |
| SCHEMBL26808251 | 0.74 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1TSHRCYP3A4TDP1 | |
| SCHEMBL11476112 | 0.74 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TSHRPSMD14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11485812-B2 | Pyranoquinazoline derivatives and naphthopyran derivatives | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2022-11-01 | — | — | US | disclosed |
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| CN-110896637-A | Pyrano quinazoline derivatives and naphthopyran derivatives | 关东化学株式会社 | 2020-03-20 | — | — | CN | disclosed |
| US-6608215-B2 | Photochromic ophthalmic or sun protection lenses, glass paneling | VISION-EASE LENS, INC. | 2003-08-19 | — | — | US | disclosed |
| US-20030092918-A1 | Oxygen-containing heterocyclic fused naphthopyrans | VISION-EASE LENS, INC. | 2003-05-15 | — | — | US | disclosed |
| WO-2003025638-A1 | OXYGEN-CONTAINING HETEROCYCLIC FUSED NAPHTHOPYRANS | VISION-EASE LENS, INC. (US) | 2003-03-27 | — | — | WO | disclosed |
| WO-1999031081-A1 | PH SENSITIVE PHOTOCHROMIC DYES | JAMES ROBINSON LIMITED (GB) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485812-B2 | Pyranoquinazoline derivatives and naphthopyran derivatives | PPOX, TYR, NQO1 | ALDH1A1 1055/4885L3MBTL1 3541/4885TSHR 4370/4885 |
| US-20030092918-A1 | Oxygen-containing heterocyclic fused naphthopyrans | NQO1, NFE2L2, NDUFV2 | ALDH1A1 202/4885L3MBTL1 4097/4885TSHR 4648/4885 |
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | PPOX, TYR, NQO1 | ALDH1A1 1152/4885L3MBTL1 3534/4885TSHR 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.