Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 12/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533729 | 0.89 | IDO1 (0.34) | IDO1CYP11B2TSHRCYP3A4 | |
| SCHEMBL10699956 | 0.89 | CYP11B2 (0.36) | IDO1CYP11B2MAPK1GCKALDH1A1 | |
| SCHEMBL27277597 | 0.89 | CYP11B2 (0.36) | IDO1CYP11B2MAPK1GCKALDH1A1 | |
| SCHEMBL10517869 | 0.85 | IDO1 (0.34) | IDO1CYP11B2MAPK1ALDH1A1MAPT | |
| SCHEMBL10515921 | 0.84 | IDO1 (0.34) | IDO1CYP11B2CYP3A4 | |
| SCHEMBL9493756 | 0.82 | CYP11B2 (0.47) | IDO1CYP11B2MAPK1GCKALDH1A1 | |
| SCHEMBL9496956 | 0.82 | CYP11B2 (0.47) | IDO1CYP11B2MAPK1GCKALDH1A1 | |
| SCHEMBL68341 | 0.82 | CYP11B2 (0.47) | IDO1CYP11B2MAPK1GCKALDH1A1 | |
| SCHEMBL29408788 | 0.82 | CYP11B2 (0.47) | IDO1CYP11B2MAPK1GCKALDH1A1 | |
| SCHEMBL9531257 | 0.79 | CYP11B2 (0.33) | CYP11B2MAPK1GCKALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |