Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533065 | 0.85 | IDO1 (0.35) | IDO1CYP11B2MAPK1ALDH1A1MAPT | |
| SCHEMBL9533729 | 0.83 | IDO1 (0.34) | IDO1CYP11B2TDO2 | |
| SCHEMBL10387930 | 0.83 | CYP11B2 (0.45) | IDO1CYP11B2MAPK1ALDH1A1MAPT | |
| SCHEMBL10515921 | 0.82 | IDO1 (0.34) | IDO1CYP11B2TDO2 | |
| SCHEMBL10699956 | 0.73 | CYP11B2 (0.36) | IDO1CYP11B2MAPK1ALDH1A1MAPT | |
| SCHEMBL27277597 | 0.73 | CYP11B2 (0.36) | IDO1CYP11B2MAPK1ALDH1A1MAPT | |
| SCHEMBL9652712 | 0.73 | IDO1 (0.41) | IDO1CYP11B2MAPK1TDO2 | |
| SCHEMBL10517057 | 0.72 | IDO1 (0.34) | IDO1ALDH1A1MAPTTDO2 | |
| SCHEMBL10596279 | 0.72 | CYP11B2 (0.35) | IDO1CYP11B2TDO2 | |
| SCHEMBL10516079 | 0.68 | TDO2 (0.34) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305332-A2 | Imidazole derivative | CIBA-GEIGY AG (CH) | 1989-03-01 | — | — | EP | claimed |