Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533065 | 0.89 | IDO1 (0.35) | IDO1CYP11B2CYP3A4TSHR | |
| SCHEMBL10596279 | 0.89 | CYP11B2 (0.35) | IDO1CYP11B2CYP3A4TDO2 | |
| SCHEMBL10517869 | 0.83 | IDO1 (0.34) | IDO1CYP11B2TDO2 | |
| SCHEMBL2819775 | 0.83 | CYP11B2 (0.45) | IDO1CYP11B2CYP3A4TDO2CCR6 | |
| SCHEMBL2819780 | 0.83 | CYP11B2 (0.45) | IDO1CYP11B2CYP3A4TDO2CCR6 | |
| SCHEMBL2822367 | 0.83 | CYP11B2 (0.45) | IDO1CYP11B2CYP3A4TDO2CCR6 | |
| SCHEMBL10515921 | 0.82 | IDO1 (0.34) | IDO1CYP11B2CYP3A4TDO2 | |
| SCHEMBL9535378 | 0.80 | CYP11B2 (0.34) | CYP11B2CCR6USP2HSD11B1TSHR | |
| SCHEMBL10648754 | 0.79 | CYP11B2 (0.41) | IDO1CYP11B2CYP3A4TDO2 | |
| SCHEMBL9804750 | 0.78 | MAPK1 (0.37) | IDO1CYP11B2CYP3A4TDO2CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |