Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604627 | 0.88 | ALDH1A1 (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7283280 | 0.81 | KMT2A (0.46) | KDM4EHPGDCYP1A2 | |
| SCHEMBL21748712 | 0.80 | ALDH1A1 (0.46) | GAAALDH1A1HTTTDP1KDM4E | |
| SCHEMBL6695501 | 0.79 | ALDH1A1 (0.41) | GAAALDH1A1HTTTDP1NPC1 | |
| SCHEMBL5902428 | 0.79 | SIGMAR1 (0.46) | ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7236982 | 0.79 | KDM4E (0.49) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL5036796 | 0.77 | ALDH1A1 (0.40) | GAAALDH1A1HTTTDP1NPC1 | |
| SCHEMBL28060046 | 0.76 | GAA (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11461137 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HTTMAPTPOLBHPGD | |
| SCHEMBL25166535 | 0.73 | TSHR (0.42) | GAAALDH1A1HTTTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |