SCHEMBL9533366

SCHEMBL9533366

COC(=O)[C@@H]1CCCN1C(=O)Cl

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.62
FKBP1A P62942 3/20 0.51
PEPD P12955 2/20 0.51
XPNPEP1 Q9NQW7 1/20 0.51
ALDH1A1 P00352 3/20 0.46
ALOX5 P09917 1/20 0.45
LMNA P02545 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PKM P14618 1/20 0.43
MMP2 P08253 1/20 0.42
ANPEP P15144 1/20 0.42
GAA P10253 1/20 0.41
CNR2 P34972 1/20 0.41
PDK2 Q15119 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10404526 0.98 POLB (0.60) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL3061683 0.94 FKBP1A (0.57) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL5965365 0.94 FKBP1A (0.57) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL30599979 0.85 POLB (0.58) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL14426613 0.85 POLB (0.58) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL3231796 0.85 POLB (0.58) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL468720 0.85 POLB (0.58) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL2037827 0.85 POLB (0.58) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL9546469 0.85 POLB (0.58) POLBFKBP1APEPDXPNPEP1ALDH1A1
SCHEMBL468719 0.85 POLB (0.58) POLBFKBP1APEPDXPNPEP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF SPARK BIOPHARMA, INC. (KR) 2025-02-06 US disclosed
EP-4365175-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF Spark Biopharma, Inc. (KR) 2024-05-08 EP disclosed
CN-117897386-A Benzopyran derivatives and uses thereof 斯帕克生物制药有限公司 2024-04-16 CN disclosed
EP-0331130-B1 CARBAMIC ACID ESTER OF SUBSTITUTED 7-HYDROXY-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES NOVO NORDISK A/S (DK) 1993-09-29 EP disclosed
US-5045540-A Amide or urea compounds containing imidazole groups WARNER-LAMBERT CO. (US) 1991-09-03 US disclosed
US-5041552-A Treatment of hypertension, heart failure, glaucoma and hyperaldosteronism WARNER-LAMBERT COMPANY (US) 1991-08-20 US disclosed
US-5017571-A Prodrugs, mental disorders NOVO NORDISK A/S (DK) 1991-05-21 US disclosed
US-4908371-A Pharmaceuticals CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed
EP-0075093-B1 PROCESS FOR THE MANUFACTURE OF L-PROLINE Degussa Aktiengesellschaft (DE) 1984-12-05 EP disclosed
US-4469876-A FROM ESTER OF L-PYROGLUTAMIC ACID DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-09-04 US disclosed
EP-0034284-B1 PIPERAZINE DERIVATIVE, PROCESSES FOR PREPARING THE SAME AND THERAPEUTIC COMPOSITIONS CONTAINING IT Tanabe Seiyaku Co., Ltd. (JP) 1983-10-05 EP disclosed
EP-0075737-A1 N-Chlorocarbonyl-amino-acid esters, process for their preparation and their use Degussa Aktiengesellschaft (DE) 1983-04-06 EP disclosed
EP-0075093-A1 Process for the manufacture of L-proline Degussa Aktiengesellschaft (DE) 1983-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF MYD88, MYADM, CD14 POLB 4767/4885FKBP1A 2480/4885PEPD 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.