Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533044 | 0.83 | ELANE (0.40) | ELANEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9533229 | 0.82 | PARP1 (0.40) | ELANEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10694920 | 0.81 | ELANE (0.47) | ELANEALDH1A1HPGDKDM4EDCPS | |
| SCHEMBL10696981 | 0.80 | PARP1 (0.38) | ELANEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9533817 | 0.80 | TNKS (0.43) | ALDH1A1HPGDKDM4E | |
| SCHEMBL9535344 | 0.77 | ELANE (0.43) | ELANEALDH1A1HPGDKDM4EDCPS | |
| SCHEMBL9534712 | 0.75 | KDM4E (0.59) | ELANEALDH1A1HPGDKDM4EDCPS | |
| SCHEMBL10694401 | 0.73 | ELANE (0.47) | ELANEALDH1A1HPGDKDM4EDCPS | |
| SCHEMBL2069228 | 0.72 | ELANE (0.49) | ELANEALDH1A1HPGDKDM4EDCPS | |
| SCHEMBL9535817 | 0.72 | PARP1 (0.44) | ELANEALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |