Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533229 | 0.86 | PARP1 (0.40) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL9533044 | 0.83 | ELANE (0.40) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL9533428 | 0.80 | ELANE (0.43) | RAB9AHPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL10696499 | 0.78 | PDE7A (0.39) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL10695051 | 0.78 | TP53 (0.46) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL10668697 | 0.72 | ALDH1A1 (0.62) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL9535817 | 0.72 | PARP1 (0.44) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 | |
| Bromide SCHEMBL11085283 | 0.71 | ALDH1A1 (0.60) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL9770658 | 0.69 | KDM4E (0.46) | PARP1HPGDSMN1; SMN2KDM4ETP53 | |
| SCHEMBL9536458 | 0.69 | NPC1 (0.45) | PARP1RAB9AHPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |