Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770665 | 0.83 | ELANE (0.42) | ELANERXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL10696099 | 0.81 | PARP1 (0.44) | ELANERXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL10695051 | 0.81 | TP53 (0.46) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9533428 | 0.81 | ELANE (0.43) | ELANEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10695759 | 0.79 | CYP1A1 (0.43) | RXFP1ALDH1A1HPGDKDM4EHRH3 | |
| SCHEMBL9534712 | 0.79 | KDM4E (0.59) | ELANERXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL10694401 | 0.76 | ELANE (0.47) | ELANEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9535344 | 0.73 | ELANE (0.43) | ELANEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9534033 | 0.72 | PKM (0.50) | ELANEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9535817 | 0.70 | PARP1 (0.44) | ELANERXFP1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |