Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535344 | 0.86 | ELANE (0.43) | ELANEMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9770718 | 0.83 | KDM4E (0.45) | ELANEMAPTPOLBSMN1; SMN2TP53 | |
| SCHEMBL9770658 | 0.81 | KDM4E (0.46) | MAPTPOLBSMN1; SMN2TP53KDM4E | |
| SCHEMBL9770716 | 0.81 | PARP1 (0.44) | ELANEMAPTPOLBSMN1; SMN2TP53 | |
| SCHEMBL9534033 | 0.77 | PKM (0.50) | ELANEMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10694920 | 0.76 | ELANE (0.47) | ELANEMAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL21653862 | 0.75 | ELANE (0.48) | ELANEMAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL10693610 | 0.75 | KDM4E (0.54) | MAPTPOLBSMN1; SMN2TP53KDM4E | |
| SCHEMBL9534712 | 0.74 | KDM4E (0.59) | ELANEMAPTSMN1; SMN2TP53KDM4E | |
| SCHEMBL10696348 | 0.73 | PDE10A (0.43) | ELANEMAPTPOLBHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |