Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA3 | P07451 | 5/20 | 0.35 |
| ▸ | CA4 | P22748 | 5/20 | 0.35 |
| ▸ | CA6 | P23280 | 5/20 | 0.35 |
| ▸ | CA5A | P35218 | 5/20 | 0.35 |
| ▸ | CA7 | P43166 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530833 | 0.99 | CA12 (0.34) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9534621 | 0.86 | CA12 (0.35) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9531284 | 0.83 | CA12 (0.35) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9530840 | 0.82 | CA12 (0.34) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9534429 | 0.82 | CA12 (0.33) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9535226 | 0.77 | DCTPP1 (0.38) | GSRTXNRD1THRBSOAT1 | |
| SCHEMBL9534628 | 0.76 | CA12 (0.35) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9532517 | 0.76 | CA12 (0.33) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10374150 | 0.72 | KDM4E (0.46) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10374153 | 0.72 | CA12 (0.43) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | claimed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | claimed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | claimed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |